Research interest

Organic synthesis and organometallic chemistry with particular emphasis on the development of new synthetic methods and mechanistic studies.

Research carreer

• 2018-          CNRS researcher – University of Poitiers / IC2MP
• 2017-2018 Post-doctoral fellow – University of Poitiers / IC2MP – Supervisor: Pr. S. Thibaudeau
• 2015-2017 Post-doctoral fellow – Université Libre de Bruxelles – Supervisor: Pr. G. Evano
• 2012-2015 PhD in Organic Chemistry – University Paris-Saclay / ICMMO – Supervisor: Pr. V. Gandon

Scientific production

• 20 publications
• 1 book chapter

Representative publications

• Access to Optically Pure Benzosultams by Superelectrophilic Activation. Michelet, U. Castelli, E. Appert, M. Boucher, K. Vitse, J. Marrot, J. Guillard, A. Martin-Mingot, S. Thibaudeau, Org. Lett. 2020, 22, 4944.
• Enantioenriched Methylene-Bridged Benzazocanes Synthesis by Organocatalytic and Superacid Activations. Beaud, B. Michelet, Y. Reviriot, A. Martin-Mingot, J. Rodriguez, D. Bonne, S. Thibaudeau, Angew. Chem. Int. Ed. 2019, 59, 1279.
• A General Copper Catalyst for Photoredox Transformations of Organic Halides. Michelet, C. Deldaele, S. Kajouj, C. Moucheron, G. Evano, Org. Lett. 2017, 19, 3576.
• Dibromoindium(III) Cation as π-Lewis Acid: Characterization of [IPr·InBr₂][SbF₆] and Catalytic Activity Towards Alkynes and Alkenes. Michelet, J.-R. Colard-Itté, G. Thiery, R. Guillot, C. Bour, V. Gandon, Chem. Commun. 2015, 51, 7401.
• Gallium-Assisted Transfer Hydrogenation of Alkenes. Michelet, C. Bour, V. Gandon, Chem. Eur. J. 2014, 20, 14488.

Publications

21. Insight into the Ferrier Rearrangement by Combining Flash Chemistry and Superacids. N. Bhuma, L. Ledebel, H. Yamashita, Y. Shimizu, Z. Abada, A. Ardá, J. Désiré, B. Michelet, A. Martin-Mingot, A. Abou-Hassan, M. Takumi, J. Marrot, J. Jiménez-Barbero, A. Nagaki, Y. Blériot, S. Thibaudeau, Angew. Chem. Int. Ed. 2020, doi: 10.1002/anie.202010175.
22. Access to Optically Pure Benzosultams by Superelectrophilic Activation. B. Michelet, U. Castelli, E. Appert, M. Boucher, K. Vitse, J. Marrot, J. Guillard, A. Martin-Mingot, S. Thibaudeau, Org. Lett. 2020, 22, 4944.
23. Enantioenriched Methylene-Bridged Benzazocanes Synthesis by Organocatalytic and Superacid Activations. R. Beaud, B. Michelet, Y. Reviriot, A. Martin-Mingot, J. Rodriguez, D. Bonne, S. Thibaudeau, Angew. Chem. Int. Ed. 2019, 59, 1279.
24. [(DPEPhos)(bcp)Cu]PF₆: A General and Broadly Applicable Copper-Based Photoredox Catalyst. H. Baguia, C. Deldaele, B. Michelet, J. Beaudelot, C. Theunissen, C. Moucheron, G. Evano, J. Viz. Exp. (JoVE) 2019, 147, e59739.
25. Direct and Selective C-H Carbamoylation of (Hetero)aromatics with TMSOTf-activated Carbamoyl Chloride. A. Uehara, S. Olivero, B. Michelet, A. Martin-Mingot, S. Thibaudeau, E. Duñach, Eur. J. Org. Chem. 2019, 1, 46.
26. A General Copper-Based Photoredox Catalyst for Organic Synthesis: Scope, Application in Natural Product Synthesis and Mechanistic Insights. C. Deldaele, B. Michelet, H. Baguia, S. Kajouj, E. Romero, C. Moucheron, G. Evano, CHIMIA 2018, 72, 621.
27. Superelectrophilic Activation in Superacid HF/SbF₅: Expanding Molecular Diversity in Nitrogen Containing Compounds Series by Fluorination. B. Michelet, H. Carreyre, F. Lecornué, A. Mingot, S. Thibaudeau, J. Fluorine Chem. 2018, 214, 68.
28. Copper-Catalyzed Photoinduced Radical Domino Cyclization of Ynamides and Cyanamides: A Unified Entry to Rosettacin, Luotonin A, and Deoxyvasicinone. H. Baguia, C. Deldaele, E. Romero, B. Michelet, G. Evano, Synthesis 2018, 50, 3022.
29. A General Copper Catalyst for Photoredox Transformations of Organic Halides. B. Michelet, C. Deldaele, S. Kajouj, C. Moucheron, G. Evano, Org. Lett. 2017, 19, 3576.
30. The Anionic Chemistry of Ynamides: a Review. G. Evano, B. Michelet, C. Zhang, C. R. Chimie, 2017, 648.
31. Catalytic Activity of Gold(I) Complexes with Hemilabile P,N Ligands. B. Michelet, D. Lebœuf, C. Bour, K. Škoch, F. Horký, P. Štěpnička, V. Gandon, ChemPlusChem 2017, 82, 442.
32. Catalytic Applications of [IPr·GaX₂][SbF₆] and Related Species. B. Michelet, S. Tang, G. Thiery, J. Monot, H. Li, R. Guillot, C. Bour, V. Gandon, Org. Chem. Front. 2016, 3, 1603.
33. Harnessing the Lewis Acidity of HFIP Through its Cooperation with a Calcium(II) Salt: Application to the aza-Piancatelli Reaction. D. Lebœuf, L. Marin, B. Michelet, A. Perez-Luna, R. Guillot, E. Schulz, V. Gandon, Chem. Eur. J. 2016, 22, 16165.
34. A Journey in the Chemistry of Ynamides: from Synthesis to Applications. G. Evano, N. Blanchard, G. Compain, A. Coste, C. S. Demmer, W. Gati, C. Guissart, J. Heimburger, N. Henry, K. Jouvin, G. Karthikeyan, A. Laouiti, M. Lecomte, A. Martin-Mingot, B. Métayer, B. Michelet, A. Nitelet, C. Theunissen, S. Thibaudeau, J. Wang, M. Zarca, C. Zhang, Chem. Lett. 2016, 45, 574.
35. Non-Innocent Behavior of Substrate Backbone Esters in Metal-Catalyzed Carbocyclizations and Friedel-Crafts Reactions of Enynes and Arenynes. B. Michelet, G. Thiery, C. Bour, V. Gandon, J. Org. Chem. 2015, 80, 10925.
36. Ca(II)-Catalyzed Alkenylation of Alcohols with Vinylboronic Acids. D. Lebœuf, M. Presset, B. Michelet, C. Bour, S. Bezzenine-Lafollée, V. Gandon, Chem. Eur. J. 2015, 21, 11001.
37. Dibromoindium(III) Cation as π-Lewis Acid: Characterization of [IPr·InBr₂][SbF₆] and Catalytic Activity Towards Alkynes and Alkenes. B. Michelet, J.-R. Colard-Itté, G. Thiery, R. Guillot, C. Bour, V. Gandon, Chem. Commun. 2015, 51, 7401.
38. Gallium(III)- and Calcium(II)-Catalyzed Meyer-Schuster Rearrangements Followed by Intramolecular Aldol Condensation or endo-Michael Addition. M. Presset, B. Michelet, R. Guillot, C. Bour, S. Bezzenine-Lafollée, V. Gandon, Chem. Commun. 2015, 51, 5318.
39. Gallium-Assisted Transfer Hydrogenation of Alkenes. B. Michelet, C. Bour, V. Gandon, Chem. Eur. J. 2014, 20, 14488.
40. Gallium Trichloride. M. Yamaguchi, S. Matsunaga, M. Shibasaki, B. Michelet, C. Bour, V. Gandon, e-EROS, 2014, 10.1002/047084289X.rn00118u.pub3
41. Cationic Gallium(III) Halide Complexes: a New Generation of π-Lewis Acids. S. Tang, J. Monot, A. El-Hellani, B. Michelet, R. Guillot, C. Bour, V. Gandon, V. Chem. Eur. J. 2012, 18, 10239.

 Oral communications

• 20^th Sigma-Aldrich Organic Synthesis Meeting 2016 (Blankenberge, Belgium)

A broadly applicable copper catalyst for photoredox transformation of organic halides

• Rencontres de Chimie Organique 2015 (Cergy-Pontoise, France)

Cationic NHC-Ga(III) and NHC-In(III) as -Lewis acids. (2^nd best communication award)

• Semaine d’Etudes de Chimie Organique 2015 (Morzine, France)

Catalysis by cationic NHC-Ga(III) and NHC-In(III) -acids.

• Journées Des Doctorants 2014 (ICMMO, Orsay, France)

Tandem transformations catalyzed by cationic NHC-Gallium(III) complexes. (Member of the organizing committee)

Education and Experience

Université de Poitiers

• Since Oct 2018 – CNRS Researcher (Chargé de Recherche Classe Normale)

Organic synthesis team

Institut de chimie des milieux et matériaux de Poitiers (IC2MP) UMR7285

• Jul 2017 – Sep 2018 – Postdoctoral position (research engineer)

Development of new superacid-promoted transformations (ANR OrgaSup).

Group of Pr. Sébastien Thibaudeau

Université Libre de Bruxelles

• Nov 2015 – Jun 2017 – Postdoctoral position (ULB fellowship)

Development of new photoinduced copper-catalyzed reactions.

Group of Pr. Gwilherm Evano

Université Paris-Saclay

• Oct 2012 – Oct 2015 – PhD in organic chemistry (MESR fellowship)

Cationic complexes of gallium(III) and indium(III): new tools for organic synthesis.

Group of Pr. Vincent Gandon

August 2014 – Visiting student

Instituto de Química, Universidad Nacional de Rosario (Argentina)

Selectivity control in Ga(III)-catalysis by substrate immobilization on solid-phase.

Group of Pr. Ernesto Mata

• Sep 2011 – Jul 2012 – Master in organic chemistry, with honours (ranked 3^rd)

January 2012 – June 2012 – Master internship

Cationic gallium in catalysis.

Group of Pr. Vincent Gandon

Heriot-Watt University (Edinburgh)

• Sep 2009 – Jul 2011 – Bachelor of Science in chemistry, with honours (upper 2^nd class)

October 2010 – April 2011 – BSc internship

Synthesis of 1,2,3,4-tetrahydopyrido[4,3-b]indoles as potential anti-cancer compounds.

Group of Pr. Dave R. Adams

Université de Poitiers

• Sep 2007 – Jul 2009 – DUT in chemistry (equivalent to a 2-year degree)

February 2009 – May 2009 – DUT internship

University Polytehnica of Bucharest (Romania)

Biopolymer thin films for photonic applications.

Group of Dr. Ileana Rău

Teaching and Supervision

• 2012 – 2015 – 64 h/year tutorial & practical teaching

Organic Chemistry (1^st and 2^nd year level)

• 2013 – 2020 – Supervision of seven intern students

Two Master 1 students and five Master 2 students

• 2018 – 2020 – Supervision of one PhD student (20%)
• 2018 – 2020 – Supervision of 3 postdocs and visiting researcher