The principal research interests of the team is to exploit the uniqueness of superacid chemistry. (Poly)protonated in superacid, molecules can be strongly activated (superelectrophilic activation). It favors the development of original synthetic methods that have no equivalent in classical organic synthesis. The direct synthesis of elaborated original compounds of high synthetic and biological value are especially targeted. In a context where chemical diversification is a vital part of the drug development process, when the conventional synthetic methods for analogue generation showed limitations, innovative superacid technology would offer a fast, versatile and revolutionary approach to generate high valued products.