Sébastien Thibaudeau

Prof. Sébastien THIBAUDEAU

+33-549454588

sebastien.thibaudeau@univ-poitiers.fr

Research interest

Organic and Bioorganic Chemistry

Superacid Chemistry – Fluorine Chemistry – Bioactive compounds synthesis –

Mechanistic investigation – Natural products modification

 

Research career

  • Sept 2015    Professor position – IC2MP UMR CNRS 7285 / University of Poitiers
  • Jan 2012      Leader of the superacid group IC2MP UMR CNRS 7285 / University of Poitiers
  • Sept 2004    Assistant professor – IC2MP UMR CNRS 7285 / University of Poitiers
  • 2003-2004  Post-doctoral fellow, Oxford University, UK. Supervisor: Pr. V. Gouverneur (Marie-Curie Fund)
  • 1999-2002  PhD in organic chemistry University of Poitiers – UMR 6514 – “Réactions en milieu superacide: fluoration et hydroxylation de composés organiques azotés, Réarrangement d’alkaloïdes de Quinquina”. Supervisor: Pr. J-C. Jacquesy

 

Teaching

  • University of Poitiers: undergraduate and master : organic synthesis

 

  Scientific production

  • 45 publications / 2 book chapters
  • 29 invited conferences: 16 in national and international symposiums and 13 in laboratory seminars

 

Five representative publications

  • “Catching elusive glycosyl cations in a condensed phase with HF/SbF5

Martin, A. Arda, J. Désiré, A. Martin-Mingot, N. Probst, P. Sinaÿ, J. Jimenez-Barbero*, S. Thibaudeau*, Y. Blériot*. Nature Chem. 2016, 8, 186-191 (highlight in Crich and Bohé Nature Chem. 2016, 8, 99).

  • “Superacid-catalyzed trifluoromethylthiolation of aromatic amines”

J. C. Bonazaba Milandou, H. Carreyre, S. Alazet, G. Greco, A. Martin-Mingot, C. Nkounkou Loumpangou, J-M. Ouamba, F. Bouazza, T. Billard,* S. Thibaudeau*. Angew. Chem. Int. Ed. 2017, 56, 169 –172 (inside cover)

  • “Keteniminium ion-initiated cascade cationic polycyclisation”

B.Theunissen, B. Métayer, N. Henry, G. Compain, J. Marrot, A. Martin-Mingot, S. Thibaudeau*, G. Evano*. J. Am. Chem. Soc. 2014, 136, 12528-12531 (cover + highlight).

  • “New superacid synthesized (fluorinated) tertiary benzenesulfonamides acting as selective hCA IX inhibitors: toward a new mode of carbonic anhydrase inhibition by sulfonamides”

B. Métayer, A. Mingot, D. Vullo, C. T. Supuran,*  S. Thibaudeau*. Chem. Commun. 2013, 49, 6015-6017 (cover).

  • Anti-Markovnikov additions to N-allylic derivatives involving ammonium–carbenium superelectrophiles

Compain, A. Martin-Mingot, G. Frapper, C. Bachmann, M-P. Jouannetaud, S. Thibaudeau*. Chem. Commun. 2012, 48, 5877-5879.

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